Chemistry: molecular biology and microbiology – Vector – per se
Patent
1997-03-28
1998-12-22
Degen, Nancy
Chemistry: molecular biology and microbiology
Vector, per se
424417, 424420, 4272133, 435 691, C12N 1564, A01N 2526, B01J 1302, C12P 2102
Patent
active
058518185
ABSTRACT:
An improvement in a method of preparing plasmid-liposome complexes for in vivo transfection is described. The improvement includes selecting a condensing agent to condense the plasmid prior to contact with the liposomes, selecting a working medium and selecting a ratio of liposome lipid to plasmid. Also disclosed are DNA plasmid-liposome complexes formed by the method.
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Hassanipour Mohammad
Huang Shi Kun
Jin Bei
Oto Edwin Kiyoshi
Degen Nancy
Dehlinger Peter J.
Mohr Judy M.
Sequus Pharmaceuticals, Inc.
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