Process for the isolation and purification of an imidazole stere

Details Process for the isolation and purification of an imidazole stere Process for the isolation and purification of an imidazole stere

1994-09-19

1996-05-21

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

5483335, 5483345, 5483121, C07D23368, C07D23390, C07D23366, C07D40110

Patent

active

055191436

ABSTRACT:
A method for the isolation and purification of an imidazole compound, useful as an angiotensin II receptor inhibitor compound or as a key intermediate therefor, from a mixture of it with its regioisomer in a solvent by treament of the mixture with a strong acid to effect selective precipitation of the desired regioisomeric imidazole salt.

REFERENCES:
patent: 4340598 (1982-07-01), Furukawa et al.
patent: 4772723 (1988-09-01), Frazer et al.
patent: 5254546 (1993-10-01), Ardecky et al.

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