Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-12-01
2000-07-18
Ford, John M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514340, 514365, 514372, 514378, 514397, 514314, 514333, 514367, 546256, 546167, 546275, 548203, 548205, 548206, 548235, 548247, 548152, A61K 31421, A61K 31422, A61K 31427, C07D26332
Patent
active
060908343
ABSTRACT:
A class of substituted oxazolyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II ##STR1## wherein R is selected from halo, mercapto, hydroxyl, lower carboxyalkylthio, lower haloalkoxy, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, lower alkoxy, aryloxy, lower alkylamino, aminocarbonyl, lower alkoxyalkyl, and lower carboxy(haloalkyl); wherein R.sup.2 is selected from lower alkyl and amino; and wherein R.sup.4 is selected from hydrido, lower alkyl, lower alkylamino, lower alkoxy and halo; or a pharmaceutically-acceptable salt thereof.
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Bertenshaw Stephen R
Graneto Matthew J
Rogier, Jr. Donald J
Talley John J
Bulock Joseph W.
Ford John M.
G.D. Searle & Co.
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