Indanylpiperidines as melatonergic agents

Details Indanylpiperidines as melatonergic agents Indanylpiperidines as melatonergic agents

Filed on

1996-04-16

Date issued

1997-12-30

Examiner

Owens, Amelia A.

Patent Class

Organic compounds -- part of the class 532-570 series

SubClass

Organic compounds

SubSubClass

Heterocyclic carbon compounds containing a hetero ring...

Other Related Categories

546206, C07D21106

Type

Patent

Status

active

Patent number

057032394

Description

ABSTRACT:
Certain indanyl piperidines are useful as melatonergic agents and can treat various CNS disorders. They are useful in treating sleep disorders and other conditions related to circadian rhythms.

REFERENCES:
Dubocovich, et al., "Antidepressant-like activity of the melatonin receptor antagonist, luzindole (N-0774), in the mouse behavioral despair test," European Journal of Pharmacology., 313-325 (1990).
Melatonin: Biosynthesis, Physiological Effects and Clinical Applications p. 359 (1993).

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