Tissue regeneration matrices by solid free form fabrication tech

Details Tissue regeneration matrices by solid free form fabrication tech Tissue regeneration matrices by solid free form fabrication tech

1994-02-23

1996-05-21

Tentoni, Leo B.

Plastic and nonmetallic article shaping or treating: processes

Stereolithographic shaping from liquid precursor

156 622, 1562728, 264 41, 264113, 264255, 264308, 264497, B29C 3508, B29C 4102, B29C 6700, B29C 6720

Patent

active

055186807

ABSTRACT:
Solid free-form techniques for making medical devices for implantation and growth of cells from polymers or polymer/inorganic composites using computer aided design are described. Examples of SFF methods include stereo-lithography (SLA), selective laser sintering (SLS), ballistic particle manufacturing (BPM), fusion deposition modeling (FDM), and three dimensional printing (3DP). The devices can incorporate inorganic particles to improve the strength of the walls forming the pores within the matrix and to provide a source of mineral for the regenerating tissue. The devices can contain tissue adhesion peptides, or can be coated with materials which reduce tissue adhesion. The macrostructure and porosity of the device can be manipulated by controlling printing parameters. Most importantly, these features can be designed and tailored using computer assisted design (CAD) for individual patients to optimize therapy.

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