Prokaryotic expression of MHC proteins

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 691, 4352523, 43525233, 4353201, 530300, 530350, 530402, C12P 2106, C12N 121, C12N 1512, C12N 1563

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active

060905875

ABSTRACT:
The present invention is directed to unglycosylated, prokaryoticauly-expressed MHC polypeptides, methods of producing these polypeptides, and complexes consisting essentially of an isolated MHC component and an antigenic peptide associated with the antigen binding site of the MHC component. These complexes are useful in treating deleterious immune responses, such as autoimmunity.

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