Substituted heterocylic 4-aminoquinoline derivatives as gastric

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546159, C07D21544, A61K 3144

Patent

active

050065351

ABSTRACT:
Substituted 4-aminoquinazoline derivatives which are inhibitors of gastric acid secretion. A compound of the invention is ethyl 8-methoxy-4-(4-methyl-3-thienyl-amino)quinoline-3-carboxylate.

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patent: 4806550 (1989-02-01), Ife et al.
Hanifin et al., J. Med. Chem. 12(5):1096-1097(1969); 4-anilino-3-quinolinecarboxylic acids and esters.
Morrison and Boyd; Organic Chemistry, Boston; Allan and Bacon, 1979, pp. 1004-1006.
Hanifin et al., "Synth. Anilino-3-Quinolinecarboxylic Acids & Esters", J. Med. Chem. vol. 12 (9) pp. 1096-1097 (1969).

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