Method for the detection of schizophrenia

Details Method for the detection of schizophrenia Method for the detection of schizophrenia

1988-03-16

1991-04-09

Kepplinger, Esther L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 4, 435 19, 436501, 436518, 560121, 424 88, G01N 3353, C12Q 144

Patent

active

050064622

ABSTRACT:
The diagnosis of schizophrenia through the detection of a phospholipase enzyme is disclosed. In this invention, a test sample from the patient can be combined with a test composition to measure phospholipase enzyme in the test sample. The sample can be read and the result compared with a scale of values found in nonschizophrenic controls.

REFERENCES:
patent: 4302447 (1981-11-01), Horrobin
Biological Abstract 84(1)9273: Gattaz et al., "Increased Plasma Phospholipase A2 in Schizophrenic Patients . . . ", Biol. Psychiatry 22(4): 421-426, 1987.
Smith et al., Principles of Biochemistry, 7th ed., (McGraw-Hill Book Company), pp. 551-552 (1983).
Thuren et al., "Fluorometric Assay for Phospholipase A2 in Serum", Clin. Chem. 31(5): 714-717 (1985).

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