Method of treating birds

Drug – bio-affecting and body treating compositions – Lymphokine

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119 68, A01K 4500, A61K 3819

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active

056981937

ABSTRACT:
A method of combatting microbial infections, including Escherichia coli and Salmonella infections, in immature birds by in ovo administration of an immune lymphokine (ILK) containing preparation in an amount effective to combat microbial infections in immature birds. A method of combatting microbial infections in immature birds by upregulating the production of endogenous Interleukin-8 (IL-8) in the bird. A method of combatting microbial infections in immature birds by in ovo administration of immune lymphokine (ILK).

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Hu, Y. et al. Disturbed Immuno-Endocrine Communication. International Archives of Allergy and Immunology. 1993. vol. 102, pp. 232-241.
M.H. Kogut, et al.; Dynamics of the Avian Inflammatory Response to Salmonellia-immune lymphokines: changes in avian blood leukocyte populations. Inflammation 18: 373-388 (1984).
G.L. Tellez, et al.; Immunoprophylaxis of Salmonella enteritidis (SE) infection by lymphokines in Leghorn chicks. Avian Dis. 37:1062-1070 (1993).
E.D. McGruder, et al.; Salmonella enteritidis immune leukocyte-stimulated soluble factors: effects on increased resistance to Salmonella organ invasion in day-old Leghorn chicks. Poultry Sci. 72:2264-2271 (1993).
M.H. Kogut and T. Slajchert; T. lymphocytes induce protection in chickens against Eimeria tenella by production of lymphokines. Immunol. Infect. Dis. 2:69-80 (1992).
J.M. Sharma and B.R. Burmester; Resistance to Marek's disease at hatching in chickens vaccinated as embryos with the turkey herpesvirus. Avian Dis. 29:134-139 (1982).
M.H. Kogut, et al.; In Ovo Administration Of Salmonella Enteritidis (SE)-Immune Lymphokines Conferred Protection Against SE Organ Infectivity In Neonatal Chicks. Poultry Science, vol. 73, Suppl. 1 (1994), p. 44.

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