Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1992-02-11
1993-09-14
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514788, 514970, 514844, 536 65, A61K 3170
Patent
active
052448800
ABSTRACT:
The invention relates to novel stable aqueous primycin solutions containing 0.5 to 1.75% by mass/volume of primycin sulfate or 2.5 to 9% by mass/volume of a complex of primycin N-methylpyrrolidone and 2 to 15% by mass/volume of pyroglutamic acid, preferably L-pyroglutamic acid or a soluble salt, preferably the sodium salt thereof as calculated for the volume of the solution to be prepared and 40 to 60% by volume of isopropanol as calculated for the volume of the solution to be prepared as well as water in an amount adding up to 100%. The stable, aqueous primycin solutions are topical antibiotics.
REFERENCES:
patent: 3920814 (1975-11-01), Bocher et al.
patent: 4064238 (1977-12-01), Bocher et al.
patent: 4782141 (1988-11-01), Dekany et al.
patent: 4789667 (1988-12-01), Makino et al.
patent: 5064815 (1991-11-01), Szentmiklosi et al.
Szentmiklosi et al, Chemical Abstract vol. 108 (1988) No. 62454h.
Hidasi Gyorgy
Juhasz Istvan
Szentmiklosi Peter
Szuts Tamas
Brown Johnnie R.
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara
Dubno Herbert
Myers Jonathan
Peselev Elli
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