Tropane derivatives

Details Tropane derivatives Tropane derivatives

1981-03-03

1982-07-27

Ramsuer, Robert W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546131, 546132, 546 91, C07D45102

Patent

active

043418953

ABSTRACT:
3.alpha.-Benzylamino-2.beta.-hydroxy-nortropanes substituted in the 8-position by an alkoxycarbonyl or alkanoyl group, useful as analgesics, are prepared by reacting the corresponding 2.beta.,3.beta.-epoxy-nortropane with enzylamine in the presence of phenol.

REFERENCES:
patent: 3120537 (1964-02-01), Archer et al.
Riley et al., J. Med. Chem. 22, 1167-1171, (1979).
Daum et al., J. Med. Chem., 15, 509-514, (1972).

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