Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1978-08-21
1980-10-21
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Dentifrices
424145, 424280, A61K 716, A61K 31365, A61K 3330
Patent
active
042294304
ABSTRACT:
A therapeutic composition is disclosed for use in improving the physiological tone of the oral tissues, which among other beneficial effects nourishes said tissues and causes them to approach normal condition. The therapeutic composition also has an antimicrobial effect on the oral microflora including those difficult to eliminate pathogenic genera known to be implicated in dental caries and periodontal disease. The therapeutic composition comprises a pharmaceutically acceptable, water soluble zinc salt and ascorbic acid or an active analog thereof. The zinc salt and the ascorbic acid are present in an amount sufficient to provide a synergistic combination which has a greater than additive antimicrobial effect on such oral genera as Actinomyces, Streptococcus, Staphylococcus, Candida, Pseudomonas and Escherichia.
REFERENCES:
patent: 1488097 (1924-03-01), Greger
patent: 2470906 (1949-05-01), Taylor
patent: 3065139 (1962-11-01), Ericsson et al.
patent: 3772431 (1973-11-01), Mlkvy et al.
patent: 3886265 (1975-05-01), Evers et al.
patent: 3888976 (1975-06-01), Mlkvy et al.
patent: 4022880 (1977-05-01), Vinson et al.
Fahim Mostafa S.
Miller Ercell L.
Fishel Grace J.
Robinson Douglas W.
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