Imidazopyridines as muscarinic agents

Details Imidazopyridines as muscarinic agents Imidazopyridines as muscarinic agents

1994-11-22

1996-11-05

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546118, 544265, A61K 31435, C07D47104

Patent

active

055718191

ABSTRACT:
The compound of the formula: ##STR1## where R.sub.1 is H, alkyl, perhaloalkyl, arylalkyl, alkenyl or alkynyl; R.sub.2 is H when R.sub.4 is other than H, and, when R.sub.4 is H, R.sub.2 is ##STR2## in which R.sub.5 is hydrogen or alkyl; R.sub.3 is hydrogen or halogen; R.sub.4 is H or ##STR3## X, Y and Z are, independently, nitrogen or carbon, at least one of X, Y or Z being nitrogen; n is 1 or 2; n.sub.1 is 0, 1, 2, 3, 4, or 5; or a pharmaceutically acceptable salt thereof are centrally active muscarinic agents.

REFERENCES:
patent: 5081253 (1992-01-01), Santilli et al.
K. Fukuda et al., TiPS 4-10 Dec. 1989 Supplement.
T. I. Bonner, TiPS 11-15 Dec. 1989 Supplement.
T. T. Soncrant et al., Psychopharmacology 112:421-427 (1993).
M. Williams, Curr. Opin. Invest. Drugs 2(5): 541-544 (May 1993).
R. T. Bartus et al., Science 217:408-417 (Jul. 1982).
Drugs of the Future 18(5):433-435 (1993).

Affiliated with

Also associated with

Rating

Imidazopyridines as muscarinic agents does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Imidazopyridines as muscarinic agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Imidazopyridines as muscarinic agents will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2015391