Method for determining by absorption of radiations the concentra

Details Method for determining by absorption of radiations the concentra Method for determining by absorption of radiations the concentra

1990-05-23

1992-03-24

Fields, Carolyn E.

Radiant energy

Invisible radiant energy responsive electric signalling

Infrared responsive

250339, 250343, 356 39, 128633, G01J 116

Patent

active

050991230

ABSTRACT:
A method and apparatus for non-invasively testing analytical substances in turbid matrices i.e. body fluids and tissues. In this method a sample is irradiated with a beam of electromagnetic energy at two alternating wavelenths, .lambda..sub.1 and .lambda..sub.2, at which the absorption by the background is the same but at one of which the radiation is absorbed by the analyte and at the other it is not. The apparatus comprises means which enable to control the input energy at .lambda..sub.1 and .lambda..sub.2 so that at the output from the sample the electric signals issuing after detection cancel in the absence of the analyte in the sample. When analyte is present cancellation no longer occurs and a signal proportional to the analyte concentration in the sample is produced. The apparatus is also designed for shifting the response back to zero when a calibrating known concentration of analyte is used as standard, thus providing a controllable zeroing base line.

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