Certain phosphinic acid derivatives having antibacterial activit

Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus acids or salts thereof

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558169, 560153, 560155, 546 22, C07F 930, C07F 932

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active

050990632

ABSTRACT:
New 3-(1-aminoalkylphosphinyl)-(2-substituted)propionic acids are described which display antibacterial activity and potentiate carbapenem antibiotics.

REFERENCES:
patent: 4147780 (1979-04-01), Dingwall
patent: 4160452 (1979-07-01), Theeuwes
patent: 4256108 (1981-03-01), Theeuwes
patent: 4265874 (1981-05-01), Bonsen et al.
patent: 4374131 (1983-02-01), Petrillo
patent: 4416833 (1983-11-01), Karanewsky et al.
patent: 4539208 (1985-09-01), Kahen et al.
patent: 4715994 (1987-12-01), Parsons et al.
F. Arndt Organic Syn. Coll. V II 165-167 p. 33 (1943).
F. R. Atherton et al., Antimibrobial Agents & Chemoth. 15. 677 (1979).
P. A. Bartlett and W. B. Kezer J. Amer. Chem. Soc. 106 4282-4283 (1979).
E. K. Baylis et al., J. Chem. Soc. Perkin Trans 1 2845-2853 (1984).
M. Bergmann & H. Schleich. Z. Physiol. Chem. Soc 205 pp. 65-75 (1966).
B. J. Campbell et al Biochem Biophys Acta 118 pp. 371-386 (1966).
Chem Abstracts, vol. 107, No. 11, No. 97134K (1987).
Chem Abstracts, vol. 107 (9) No. 78205d (1987).
Chaiet et al., J. Antibiotics 37 (3) 207-210 (1984).
Gundermann et al., Chem. Bes. 94 3254 (1961).
F. M. Kahan et al., J. Antimicrobial Chemo. 12, Suppl. D, 1-35 (1983).
Lesiak et al., Polish J. Chem. 53 327 (1979).
Neuhaus J. Biol. Chem., 778 (1962).
F. C. Neuhaus & W. P. Hammes, Pharm. Ther. 14 265-319 (1981).
F. C. Neuhaus & J. L. Lynch Biochemistry 3 471-480 (1964).
F. C. Neuhaus et al., Biochemistry 8 5119-5124 (1969).
A. Rahman et al., Tetrahedron 36 1063-1070 (1980).
E. D. Thorsett et al., (Merck & Co., Inc. Proc. Natl. Acad. Sci. U.S.A. vol. 79 2176-2180 (Apr. 1982).
J. K. Thottathil et al., Tetrahedron Lett. 25 4737-40, 4741-44 (1984).

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