Process of making 2,5-diaryl tetrahydrofurans and analogs thereo

Details Process of making 2,5-diaryl tetrahydrofurans and analogs thereo Process of making 2,5-diaryl tetrahydrofurans and analogs thereo

1990-06-29

1992-03-24

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549222, 549475, 549496, 549497, 549498, 549499, 549500, 549501, 549502, 549504, C07D30702, C07D49800

Patent

active

050990330

ABSTRACT:
The present invention is directed to a process of making tetrahydrofuran of the formula (D) ##STR1## resulting in 2,5-diaryltetrahydrofuran PAF antagonists of pharmaceutically acceptable purity.

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M. M. Ponpipom, et al, Biochem. & Biophys. Res. Com. 150, 1213 (1988).
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H. Stetter, et al., Agnew. Chem. Int. Ed. Eng. 85, 89 (1973) & German equivalent H. Stetter, et al., Agnew. Chem. Int. Ed. Eng. 12, 81 (1973).

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