Process for the synthesis of 4-amino-1,2,4-(4h)triazole derivati

Details Process for the synthesis of 4-amino-1,2,4-(4h)triazole derivati Process for the synthesis of 4-amino-1,2,4-(4h)triazole derivati

1989-12-19

1992-03-24

Morris, Patricia L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D24914

Patent

active

050990284

ABSTRACT:
A process for preparing a 4-amino-1,2,4-(4H)triazole derivative compositions having the formula ##STR1## wherein R is hydrogen or an alkyl group containing from 1 to about 10 carbon atoms, which alkyl group can be additionally substituted by one or more aryl, heteroaryl, hydroxy, or alkenyl substituents, comprising the step of reacting hydrazine or an aqueous hydrazine solution with a carboxylic acid having the formula RCO.sub.2 H in the presence of an insoluble polymer containing acidic functional groups sufficiently strong to cause the reaction to proceed under mild conditions to produce a product of high yield and purity.

REFERENCES:
Valcke et al., Proc.-Annu. Meet. Am. Wood-Preserv. Assoc. 1985, 81, 196.
Jager, Pestic. Chem. Hum. Welfare Environ., Proc. Int. Congr. Pestic Chem., 5th, vol. 1, pp. 55-65.
Kucharski and Chodan, Zasz. Nauk, Akad. Roln-Tech. Olsztynie, Roln., 36, 109-116 (Chem. Abstr., 101, 129600 (1984)).
Organic Syntheses (vol. 24, p. 12, 1944).
Herbst and Garrison (J. Org. Chem., 18, 872 (1953)).
Mizushima et al., (Japan Pat. No. 71 35,056 (1971), Chem. Abstr., 76, 3867 (1972).
Jaromir and Jaromir (Czech. Patent 216,554, (1984), Chem. Abst. 103, 160520 (1985).
Krieble et al., "Amide Hydrolysis with etc." JACS (1938) 60 2976.
J. March, Advanced Organic Chemistry, 3rd Ed., Wiley-Interscience, 1985, p. 338.
B. C. Challis et al., The Chemistry of Amides, Ed. J. Zabicky, Interscience, 1970, p. 816.
Krysin et al., "Amino derivatives of 1,2,4-triazole," CA 84:90156s 1976.
Socha et al. II, "4-Amino-4H-1,2,4-triazole," CA 101:191930q 1984.
Socha et al. III, "4-Amino-4H-1,2,4-triazole," CA 105:208889r.

Affiliated with

Also associated with

Rating

Process for the synthesis of 4-amino-1,2,4-(4h)triazole derivati does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the synthesis of 4-amino-1,2,4-(4h)triazole derivati, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the synthesis of 4-amino-1,2,4-(4h)triazole derivati will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2011658