Inhibitors of human plasmin derived from the Kunitz domains

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 691, 4352523, 4353201, 424 9464, 514 12, 530300, C12P 2106, C12N 120, C12N 1500, A61K 3848

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061034991

ABSTRACT:
This invention provides: novel proteins, which are homologous to the first Kunitz domain (K1) of lipoprotein-associated coagulation inhibitor (LACI), and which are capable of inhibiting plasmin; uses of such novel proteins in therapeutic, diagnostic, and clinical methods; and polynucleotides that encode such novel proteins.

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