Process for determining parameters of interest in living organis

Details Process for determining parameters of interest in living organis Process for determining parameters of interest in living organis

1989-08-02

1992-03-24

Pellegrino, Stephen C.

Surgery

Truss

Pad

128637, 128DIG13, 604 50, H61B 500

Patent

active

050978349

ABSTRACT:
In order to determine at least one parameter of interest in a living organism, a perfusion fluid is directly introduced in the tissues. After its partial balancing by the tissue parameter of interest, the perfusion fluid is collected and analyzed for the parameter of interest, as well as for endogenous or exogenous marker properties indicative of the degree of interaction between the perfusion fluid and the tissue, in such a way that the parameter of interest can be determined with the help of such characteristic properties. Contrary to usual processes, used exclusively inside blood vessels or other body cavities filled with liquid, this process creates in the tissues, i.e. in the closed cellular structure, a previously inexistent cavity, in which the perfusion fluid introduced in the tissue interacts directly with the organic tissue, with no intervening membranes. The transfer of the measurement site into the tissue completely eliminates the risk of the thromboses and embolies, besides strongly reducing the risk of infection.

REFERENCES:
patent: 4221567 (1980-09-01), Clark et al.
patent: 4253456 (1981-03-01), Schindler et al.
patent: 4516580 (1985-05-01), Polanyi
patent: 4632119 (1986-12-01), Reichstein
patent: 4633878 (1987-01-01), Bombardieri
patent: 4761371 (1988-08-01), Bell et al.
patent: 4774955 (1988-10-01), Jones

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