Separation of coformycin and its related nucleosides

Details Separation of coformycin and its related nucleosides Separation of coformycin and its related nucleosides

1978-02-27

1979-04-24

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 26, C07H 1700, A61K 3170

Patent

active

041513479

ABSTRACT:
A known nucleoside, coformycin and its related substances such as isocoformycin, 2'-deoxycoformycin and formycins present as a mixture of them may be separated from each other when an aqueous solution containing them is chromatographed on a column of a cation-exchanger having partially activated carboxylic groups as the ion-exchange function with using water or a buffer solution as the developing solvent.

REFERENCES:
patent: 3923785 (1975-12-01), Ryder et al.
patent: 3959257 (1976-05-01), Umegawa et al.

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