Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Patent
1994-10-03
1996-12-17
Wong, Leslie
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
204193, 204194, 252302, 264 41, 424450, 514143, C12Q 102
Patent
active
055852491
ABSTRACT:
Lipid bilayers which incorporate poly-3-hydroxybutyrate/polyphosphate ion channels. The ion channels are preferably purified polyhydroxybutyrate polyphosphate complexes extracted from organisms or prepared from the individual constituents which have been size selected. The bilayers are useful for testing the affect of various molecules and ions on the channel which correlates to the in vivo result. The bilayers are useful for transporting the channels into cells or other bilayers.
REFERENCES:
patent: 4891324 (1990-01-01), Pease et al.
patent: 5328847 (1994-07-01), Case et al.
Reusch Soc. Exp. Biol & Med. 19, pp. 377-381 (1989).
Reusch, R. N. et al., J. Bacteriol. 156, 778-788 (1983).
Reusch, R. N. et al., J. Bacteriol. 168, 553-562 (1986).
Reusch, R. N. et al., Can. J. Microbiol. 33, 435-444 (1987).
Reusch, R. N. et al., Proc. National Acad. Science 85, 4176-4180 (1988).
Reusch, R. N., FEMS Microbiology Rev. 103, 119-130 (1992).
Hess, P. et al., Nature. 309, 453 (1984).
Almers, W. et al., J. Physiol. 353, 585 (1984).
Phospholipid Handbook, Marcel Dekker, Inc., New York 1-22 and 603-637 (1993).
Hannahan, D., J. Mol. Biol. 166, 557-580 (1983).
RRC, New. Liposomes a Practical Approach, IRL Press, pp. 1 to 104 (1990).
Tsien, et al., Ann. Rev. Biophys. Biophys. Chem. 16, 265, (1987).
MacCallum, J. R. et al., Polymer Electrolyte Reviews, Elsevier Applied Science, N.Y. pp. 23-37 (1987).
Watanabe, et al., Macromolecules 17, 2908-2912 (1984).
Corbridge, D.E.C., Stud. Inorg. Chem. 6:170-178 (1985).
Martin, R. B., Bioinorganic chemistry of magnesium. In "Metal Ions in Biological Systems", Sigel, H. and Sigel, A., eds., 26:1-13 (1990).
Board of Trustees operating Michigan State University
McLeod Ian C.
Wong Leslie
LandOfFree
Polyhydroxybutyrate and polyphosphate membranes with channels does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Polyhydroxybutyrate and polyphosphate membranes with channels, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polyhydroxybutyrate and polyphosphate membranes with channels will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1990410