Methods for treating disease states using oxidized lipoproteins

Details Methods for treating disease states using oxidized lipoproteins Methods for treating disease states using oxidized lipoproteins

1993-01-13

1994-11-22

Prebilic, Paul

Surgery

Blood drawn and replaced or treated and returned to body

604 5, 604 6, 604 51, 128898, A61M 3700

Patent

active

053664400

ABSTRACT:
The present invention relates to treating disease states in a living patient using oxidized lipoproteins, preferably low density peroxidized lipoproteins. Methods and apparatus are provided for preparing the oxidized lipoproteins. It has been discovered that diseased cells, characterized by an increased number of lipoprotein receptors or an enhanced ability to take up lipoproteins are more susceptible than healthy cells to the the cytotoxic effect of oxidized lipoproteins. Oxidized lipoproteins are used to treat disease states such as cancer, malaria and viral infections such as acquired immunodeficiency syndrome (AIDS). Proton and carbon-13 NMR spectroscopy is used to measure the degree and effect of treatment with oxidized lipoproteins.

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