Novel analogs of prostaglandins with 4-oxo-thiazolidinyl nucleus

Details Novel analogs of prostaglandins with 4-oxo-thiazolidinyl nucleus Novel analogs of prostaglandins with 4-oxo-thiazolidinyl nucleus

1976-05-24

1977-05-10

Randolph, John D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424263, 424270, 2602471M, 260268H, 260295AM, 260301, 2603067R, 2603451, 2603457, 2603473, 2603477, 260468D, 260483, C07D40102, C07D27702

Patent

active

040227944

ABSTRACT:
This invention relates to novel 9-thia-, 9-oxothia-, and 9-dioxothia-11-oxo-12-azaprostanoic acid compounds, salts, and derivatives thereof and also to processes for the preparation of such compounds. These compounds have prostaglandin-like biological activity and are particularly useful as renal vasodilators, as platelet aggregation inhibitors, and for the treatment of certain autoimmune diseases.

REFERENCES:
Ambrus et al, Prostaglandins, vol. 10, pp. 661-666 (Oct. 1975).

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