Triazolo[4,3-d][1,4]benzodiazepine-6-ones

Details Triazolo[4,3-d][1,4]benzodiazepine-6-ones Triazolo[4,3-d][1,4]benzodiazepine-6-ones

1975-01-06

1977-05-10

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424269, C07D47114, C07D40114, C07D41306

Patent

active

040227650

ABSTRACT:
Compounds having the structure ##STR1## wherein R.sub.1 is hydrogen, alkyl, phenyl, or benzyl; R.sub.2 is hydrogen or alkyl; R.sub.3 is hydrogen, alkyl, haloalkyl, cyanoalkyl, trifluoromethyl, phenyl, benzyl, ##STR2## OR --(CH.sub.2).sub.n --NR.sub.5 R.sub.6 ; R.sub.4 is hydrogen, halogen, nitro, cyano, trifluoromethyl, alkyl, alkoxy, or alkylthio; R.sub.5 and R.sub.6 are the same or different and are hydrogen or alkyl or R.sub.5 and R.sub.6 together with the nitrogen atom to which they are attached form a five or six membered heterocyclic ring; and n is 1, 2, 3 or 4; are useful as anti-inflammatory agents.

REFERENCES:
patent: 3869450 (1975-03-01), Kathawala
patent: 3894011 (1975-07-01), Vogt et al.
patent: 3895005 (1975-07-01), Vogt et al.

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