Pharmaceutical compositions and methods of inhibiting H-1 and H-

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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424250, 424263, 424267, 424270, 424273R, 424274, 424330, A61K 3140, A61K 3144, A61K 31135, A61K 31415

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active

041043820

ABSTRACT:
Pharmaceutical compositions and methods of inhibiting H-1 and H-2 histamine receptors by administering an antihistamine and an H-2 histamine receptor inhibitor. Exemplary of the antihistamine in the compositions and methods of this invention is mepyramine and exemplary of the H-2 histamine receptor inhibitor is N-cyano-N'-methyl-N"-[2-((4-methyl-5-imidazolyl)-methylthio)ethyl]guanidin e.

REFERENCES:
patent: 3876647 (1975-04-01), Durant et al.
patent: 3920822 (1975-11-01), Durant et al.
patent: 3968216 (1976-06-01), Black et al.

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