Substituted 1-alkylthiophenyl-2,3,4,5-tetrahydro-1H-3-benzazepin

Details Substituted 1-alkylthiophenyl-2,3,4,5-tetrahydro-1H-3-benzazepin Substituted 1-alkylthiophenyl-2,3,4,5-tetrahydro-1H-3-benzazepin

1977-01-19

1978-08-01

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260239BB, 2605706, A61K 3155, C07D22316

Patent

active

041043790

ABSTRACT:
A group of 1-phenyl-1H-3-benzazepines whose structures are characterized by having a functional thio containing group on the 1-phenyl moiety and which have pronounced peripheral and diminished central dopaminergic activity. This activity is manifested in an anti-hypertensive effect in humans. Particular species of this group include 6-chloro-7,8-dihydroxy-1-p-methylthiophenyl-2,3,4,5-tetrahydro-1H-3-benzaz epine and its derivatives which have dopaminergic activity.

REFERENCES:
patent: 3393192 (1968-07-01), Walter et al.
patent: 3483185 (1969-12-01), Tokolics et al.
patent: 4011319 (1977-03-01), Kaiser et al.
patent: 4052506 (1977-10-01), Kaiser et al.

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