Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-09-24
1995-11-07
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549 57, 549 58, A61K 3138, C07D33366
Patent
active
054648637
ABSTRACT:
An N-heteroaryl-N'-phenylurea derivative represented by the general formula (I): ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 are as defined in the description of the specification which is useful as a prophylactic and therapeutic agent for hypercholesterolemia, atherosclerosis and diseases caused by them.
REFERENCES:
patent: 4113731 (1978-09-01), Winters et al.
patent: 4157399 (1979-06-01), Sauter
Farmaco, Edizione Scientifica, vol. 34, 1979, Pavia It, pp. 507-517, G. Winters et al. `Synthesis and Biological Activities of Some Indolo[2,3-c]isoquinoline Derivatives` p. 516, paragraph 2, table II.
Chemical Abstract vol. 90, 87163k (1978).
Chemical Abstract vol. 91, 175235m (1979).
Horiuchi Kenji
Matsui Yoshimitsu
Nagamine Masashi
Yamamoto Kenji
Yoshida Masanori
Cebulak Mary C.
Nihon Nohyaku Co. Ltd.
Raymond Richard L.
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