Pharmaceutically acceptable anthracene compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ketone doai

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A61K 3112

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active

055786464

ABSTRACT:
The invention concerns the use of bis-anthracene compounds isolated from Karwinskia humboldtiana in therapy. The compounds of the invention are selective with a high margin of safety relative to malignant tumor cells and therefore are suitable in particular in the treatment of liver, lung and colon carcinomas and further in the treatment of viral diseases.

REFERENCES:
patent: 4283390 (1981-08-01), Koch et al.
patent: 4670265 (1987-06-01), Sydiskis et al.
Chemical Abstracts, vol. 107, 1987, Abstract No. 230651; Guerrero et al.; Toxicon; vol. 25, No. 5, pp. 565-568; 1987.
Chemical Abstracts, vol. 110, 1989, Abstract No. 228622e; Kitanaka et al.; Chem. Pharm. Bull., vol. 37, No. 2, 1989; pp. 511-512.
Chemical Abstracts, vol. 80, 1974; Abstract No. 12461r; Steglich et al.; Zeitung Naturforschung, Teil C, vol. 28, No. 5-6, 1973, pp. 255-259.
Chemical Abstracts, vol. 80, 1974; Abstract No. 12463t; Steglich et al.; Zeitung Naturforshcung, Teil C, vol. 28, No. 5-6, 1973, pp. 354-355.
Chemical Abstracts, vol. 78, 1973; Abstract No. 4001j; Steglich et al.; Phytochemistry, vol. 11, No. 11, 1972, pp. 3299-3304.
"Hagers Handbuch der Pharmazeutischen Praxis," Vierte Neuausgabe, V. Band Chemikalien und Drogen (H-M).
D. L. Dreyer, I. Aral, C. D. Bachman, W. R. Anderson, Jr., R. G. Smith and G. D. Daves, Jr., "Toxins Causing Noninflammatory Paralytic Neuronopathy. Isolation and Structure Elucidation," J. Am. Chem. Soc., 97:17 (Aug. 20, 1975).
M. Guerrero, A. Pineyro and N. Waksman, "Extraction and Quantification of Toxins from Karwinskia humboldtiana (Tullidora), Toxicon", vol. 25, No. 5, pp. 565-568 (1987).
M. V. Bermudez, D. Gonzalez-Spencer, M. Guerrero, N. Waksman and A. Pineyro, "Experimental Intoxication with Fruit and Purified Toxins of Buckthorn (Karwinskia humboldtiana), Toxicon", vol. 24, Nos. 11-12, pp. 1091-1097 (1986).
N. Waksman, L. Martinez, "Chemical and Toxicological Screening in Genus Karwinskia (Mexico)," Rev. Latinoamer. Quim., vol. 20, No. 1, pp. 27-29 (1989).
International Congress on Natural Products Research, American Society of Pharmacognosy & Japanese Society of Pharmacognosy, 29th Annual Meeting of the American Society of Pharmacology (Jul. 17-21, 1988).
S. Kitanaka and M. Takido, "Studies on the Constituents of the Roots of Cassia torosa. II. The Structures of Two Dimeric Tetrahydroanthracenes," Chem. Pharm. Bull., vol. 38, No. 5, pp. 1292-94 (1990).
Omura et al 90 CA:119686b 1979.
Kakinuma et al 93CA:233347d 1980.
Roth et al 114CA:17555e 1990--Jun. 13 1990.
Konoshima et al 113CA:204402u 1989.
Kitanaka et al 113CA:108782x 1990.
Toshio et al 112CA:84202j 1989.
Takito et al 110CA:82476m 1987.
Dagne et al 109CA:22736R 1987.
Avery's Dry Treatment, 3rd Edition 1988, pp. 1039-1055.

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