Immunosuppressive agent

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549294, A61K 3135

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active

053149114

ABSTRACT:
The present invention relates to a compound represented by the formula I: ##STR1## which was isolated from the culture of Streptomyces prunicolor PA-48153 and has biological activity such as immunosuppressive activity, antitumor activity and antifungal activity.

REFERENCES:
patent: 4680416 (1987-07-01), Hokanson et al.
patent: 4918100 (1990-04-01), Hokanson et al.
Patent Abstracts of Japan, vol. 12, No. 438 (C-544)(3285), Nov. 17, 1988, JP-A-63 165 323, Jul. 8, 1988.
Derwent Publications Ltd., AN 89-036772/05, Jun. 11, 1987, JP-146767, Dec. 19, 1988.
Gan to Kagaku Ryoho, 11(12) Part II, pp. 2674-2680, 1984.
Derwent Publications Ltd., AN 88-231647/33, Jul. 3, 1986, JP-157385, Jul. 8, 1988.
Derwent Publications Ltd., AN 88-238170/34, Jun. 11, 1987, JP-146766, Jul. 14, 1988.

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