Dry reagent for creatinine assay

Details Dry reagent for creatinine assay Dry reagent for creatinine assay

1994-09-26

1995-11-07

Housel, James C.

Chemistry: analytical and immunological testing

Heterocyclic carbon compound

Hetero-n

436534, 436518, 435 71, 435973, G01N 33546, G01N 3353, G01N 33557

Patent

active

054647770

ABSTRACT:
A method for the determination of protein and creatinine in urine. An organic acid, in the form of its lithium salt, is dried onto a suitable substrate in the second reaction zone of a reaction vessel having a first reaction zone for the immunometric determination of the protein and a second reaction zone for the colorimetric determination of creatinine. After completion of the immunometric determination of the protein the dried organic salt is contacted with the urine containing creatinine resulting in solubilization of the organic acid salt as creatinine reactive reagent thereby facilitating the colorimetric determination of the creatinine.

REFERENCES:
patent: 5385847 (1995-01-01), Yip
Benedict et al, J. Biol. Chem., vol. 114, 1936.

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