Fibrous assembly of peptide lipid and method for the preparation

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lipoproteins – e.g. – egg yolk proteins – cylomicrons – etc.

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530331, 530333, 530343, 514 18, 514 19, C07K 1600, A61K 3800

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active

06136956&

ABSTRACT:
Disclosed is a fine fibrous assembly having a molecular structure of a bola-form peptide lipid containing L- or D-valine residues which can be obtained by spontaneous crystallization precipitation when an aqueous solution of the peptide lipid compound of the general formula ##STR1## in which Me is a methyl group, the subscript m is 1, 2 or 3 and the subscript n is a positive integer in the range from 6 to 18, in the form of an alkali metal salt is kept standing over days under an atmosphere of a saturated vapor over a dilute aqueous solution of a vaporizable acid such as acetic acid.

REFERENCES:
O. Traet al., J. Am. Chem. Soc., 119, 9120-9124 (1997).

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