Inosine-guanosine kinase

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435196, 4352523, 43525233, 4353201, 536 232, C12N 1555, C12N 916, C12N 1563, C12P 1932

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active

057563152

ABSTRACT:
The present invention relates to an inosine-guanosine kinase which catalyzes the reaction of forming 5'-inosinic acid (5'-IMP) from inosine and adenosine triphosphate (ATP) or deoxyadenosine triphosphate (dATP) and the reaction of forming 5'-guanylic acid (5'-GMP) from guanosine and ATP or dATP.

REFERENCES:
Hove-Jensen, J. Gen. Microbiol., 135 (1989) 1263-73.
Pierre and LePage, Formation of Inosine 5'-Monophosphate by a Kinase . . . Proc. Soc. Exp. Biol. Med. 127: 432-440 (1968).
No new references are cited. Please see PTOL 892 attached to paper 11.
Jochimsen et al (1975) Mol. Gen-Genct 143:85-91. "Location on the chromosome of E. coli of genes governing purine metabolism . . . ".
Kohara et al (1987) Cell 50:495-508. "The physical map of the whole E. coli chromosome: Application of a new strategy . . . ".
Maniatis et al Mol. Cloning Cold Spring Press (1982).
Combes et al Plant Phys Biochem (Paris) 27(5) 729-36 1989.
LePage et al. Pro Soc. Exp. Md. 127(1) 237-244 (1968).
Maniatis et al. Molecular Cloning Cold Springs Harbor Press (1982).
Combes et al Plant Physiol. Biochem (Paris) 27(5) 729-36 (1989).
LePage et al. Pro. soc. Exp. Med 127(1) 239-44 (1968).

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