Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1994-05-24
1995-11-07
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424474, 424475, 424476, 424481, 424482, 424468, A61K 930, A61K 932, A61K 934, A61K 936
Patent
active
054646332
ABSTRACT:
Pharmaceutical tablets releasing the active substance after a definite period of time, consisting of: a core containing the active substance and polymeric substances which swell and/or gel and/or erode on contact with water or with aqueous liquids; a layer applied externally to said core, suitable to prevent the immediate release of the active substance contained in the core and to allow the release of said active substance after a definite period of time, consisting of natural and/or synthetic polymeric materials of the class of the hydrophilic polymers which erode and/or gel and/or dissolve in an aqueous medium; a possible gastroresistant and enterosoluble coating.
REFERENCES:
patent: 4726951 (1988-02-01), Panoz et al.
patent: 4756911 (1988-07-01), Drost et al.
Proced. Intern. Symp. Rel. Bioact. Mater., 12, pp. 45-46 (1985).
Techniques of Solubilization of Drugs, S. H. Yalkowsky, Ed. Marcel Dekker Inc. NY (1985) pp. 1,15,91, 135 & 159.
Diabetes, vol. 35, (1986) pp. 217-221.
Conte Ubaldo
La Manna Aldo
Maggi Lauretta
Jagotec AG
Page Thurman K.
Spear James M.
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