Use of transglutaminases as immunosuppressants

Details Use of transglutaminases as immunosuppressants Use of transglutaminases as immunosuppressants

1994-09-22

1995-11-07

Stone, Jacqueline M.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

424 9464, 514 2, 514 21, 514885, 530381, 530384, A61K 3848, A61K 3855

Patent

active

054646154

ABSTRACT:
A description is given of the possibility of using transglutaminases in a process for the preparation of an immunosuppressant.
Additionally described is a pharmaceutical containing a transglutaminase and a plasminogen activator inhibitor.

REFERENCES:
patent: 4327086 (1982-04-01), Fukushima et al.
patent: 4414976 (1983-11-01), Schwarz et al.
G. Dickneite, et al "The Immunosuppressive Properties of 15-Deoxysperqualin and Its Effects on Experimental Skin and Islet Cell Transplantation," Recent Advances in Chemotherapy, Anticancer Section 2, Proceedings of the 14th International Congress of Chemotherapy, Kyoto, pp. 949-950 1985.
Suzuki et al, Thrombosis and Haemostasis, vol. 58(1) Jul. 1987, abstract 509.
"Report of the Meeting of the Subcommittee on Fibrinolysis, Jerusalem, Israel, Jun. 2, 1986", Thromb. Haem., 56, 415-416.

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