Suppressory compositions against hepatic metastases of tumors

Details Suppressory compositions against hepatic metastases of tumors Suppressory compositions against hepatic metastases of tumors

1995-03-27

1996-09-03

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514100, A61K 3170, A61K 31665

Patent

active

055523897

ABSTRACT:
The present invention provides suppressory compositions against hepatic metastases of tumors which comprise a phosphoric acid diester compound of the formula: ##STR1## (wherein R.sub.1 and R.sub.2 each is the same as or different from the other and represents hydrogen or methyl) or a pharmacologically acceptable salt thereof.

REFERENCES:
Patent Abstracts of Japan, vol. 014 No. 543, Nov. 30, 1990 & JPA02229168, Sep. 11, 1990 Abstract.
Patent Abstracts of Japan, vol. 014, No. 543, Nov. 30, 1990 JPA02229169, Sep. 11, 1990 Abstract.
Database WPI, Week 8731, Derwent Publications Ltd, London, GB., AN87-218325 & JP-A 62145019 (Senju Seiyaku KK), Dec. 19, 1985 (abstract).
Arzneimittelforschung, vol. 42, No. II, 1992, pp. 1072-1074 In Vitro Studies on the Influence of L-Ascorbic Acid . . . Phospholipase A2 Activity.
Proceedings of the Annual Meeting of the American Association for Cancer Research, vol. 34, Mar. 1993, pp. 570-571, Kohn, E. C. et al. `Signal Transduction Therapy of Metastasis`.

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