Recombinantly produced human membrane cofactor protein (MCP) pha

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 12, 530350, 530395, 530380, 530829, 435 691, A61K 3817, C07K 14435, C07K 14705

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active

055523811

ABSTRACT:
Human membrane cofactor protein (MCP), a protein involved in regulation of complement activity, has been purified to homogeneity. The cDNAs encoding six isoforms of this protein have been retrieved and permit deduction of the complete amino acid sequences and the recombinant production of proteins with this activity. Pharmaceutical compositions in which MCP is the active ingredient for use in treating autoimmune diseases, antibody preparations for diagnosis, and DNA probes are also disclosed.

REFERENCES:
patent: 5135916 (1992-08-01), Sims et al.
patent: 5159063 (1992-10-01), Hammer et al.
patent: 5179198 (1993-01-01), Okada et al.
Birmingham et al, J. Immunol. 142:3140-3144 (May 1989).
Seya, Hok. Igaku Zasshi 63:259-268 (Mar. 1988).
Seya et al, Biochem. J. 264:581-588 (Dec. 1989).
Hara et al, Clin. Exp. Immunol. 89:490-494 (Sep. 1992).
Stites et al, Basic And Clinical Immunology, pp. 136, 137, 410 (1991).
Holers et al., Immunol. Today (1985) 6(6):188-192.
Ross et al., Adv. Immunol. (1985) 37:217-267.
Atkinson et al., Immunol. Today (1987) 8(7&8):212-215.
Cole et al., Proc. Natl. Acad. Sci. (1985) 82:859-863.
Seya et al., J. Exp. Med. (1986) 163:837-855.
Ballard et al., J. Immunol. (1987) 138(11):3850-3855.
Seya et al., Eur. J. Immunol. (1988) 18:1289-1294.
Lublin et al., Ann. Rev. Immunol. (1989) 7:35-58.
McNearney et al., J. Clin. Invest. (1989) 84:001-008.
Lublin et al., Current Topics in Microbiology and Immunology J. D. Lambris, ed., (1989) 153:123-145.
Medof et al., Proc. Natl. Acad. Sci. (1987) 84:2007-2011.
Caras et al., Nature (1987) 325:545-549.
Goujet-Zalc et al., Cellular Immunol. (1987) 109:282-294.
Wong et al., J. Immunol. (1985) 134:4048-4056.
Schneider et al., J. Immunol. (1981) 290:789-792.
Cui et al., FASEB Journal (1989) 3:A500, Number 1594.
Yu et al., J. Clin. Invest. (1986) 78:494-501.
Caras et al., Science (1987) 238:1280-1283.
Seya et al., Complement (1987) 4:255.
Lublin et al., J. Exp. Med. (1987) 165:1731-1736.
Lublin et al., J. Exp. Med. (1988) 168:181-194.
Ballard et al., J. Immunol. (1988) 141(11):3923-3929.
Seya et al., Biochem. J. (1989) 264:581-588.
Stafford et al., Proc. Natl. Acad. Sci. USA (1988) 85:880-884.
Bora et al., J. Exp. Med. (1989) 169:597-602.
Farries et al., Complement & Inflammation (1990) 7:30-41.
Hourcade et al. Progress in Immunology (1989) VII:171-177.
Reid et al., Immunol. Today (1986) 7(7&8):230-234.
Purcell et al., Immunology (1990) 70:155-161.
Kim, J. Biol. Chem. (1989) 264(17):9780-9784.
Hourcade et al., Adv. Immunol. (1989) 45:381-416.

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