Human prohormone convertase 4

Details Human prohormone convertase 4 Human prohormone convertase 4

1999-08-06

2000-10-03

Carlson, Karen Cochrane

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

536 232, 536 234, 4352523, 4353201, C12N 964, C12N 120, C12N 1500, C07H 2104

Patent

active

061271624

ABSTRACT:
The present invention provides polynucleotide and polypeptide molecules for a novel human prohormone convertase 4. The polynucleotides encoding human prohormone convertase 4, are located on chromosome 19, and may, for example, be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein and antibodies thereto.

REFERENCES:
Seidah et al., Biochimie 76: 197-209, 1994.
Smeekens, Bio/Technology 11: 182-196, 1993.
Nakayama et al., J. Biol. Chem. 267: 5897-5900, 1992.
Seidah et al., Molecular Endocrinology 6: 1559-1570, 1992.
Mbikay et al, Genomics 26: 123-129, 1996.
Mbikay et al., Genomics 20: 231-237, 1994.

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