1-[(Substituted-naphthyl)ethyl]-imidazole derivatives

Details 1-[(Substituted-naphthyl)ethyl]-imidazole derivatives 1-[(Substituted-naphthyl)ethyl]-imidazole derivatives

1979-03-09

1981-07-07

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548336, 548341, A61K 31415, C07D23360, C07D40506

Patent

active

042774861

ABSTRACT:
Compounds of the formula ##STR1## wherein m is the integer 1, 2 or 3; R is independently selected from the group C.sub.1 to C.sub.6 alkyl, C.sub.1 to C.sub.6 alkoxy, halo, trifluoromethyl and hydroxy when m is the integer 1, 2 or 3 and methylenedioxy when m is the integer 2; Z is hydroxymethylene, esterified hydroxymethylene, alkoxymethylene, alkylthiomethylene, carbonyl, or ketal-, thioketal- or hemithioketal- protected carbonyl, and the pharmaceutically acceptable acid addition salts thereof, are useful as anticonvulsants, anti-secretory agents and spermatocides.

REFERENCES:
patent: 4085209 (1978-04-01), Miller et al.
patent: 4141908 (1979-02-01), Heeres
patent: 4150153 (1979-04-01), Walker
patent: 4156008 (1979-05-01), Heeres
patent: 4172141 (1979-10-01), Walker

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