Preparation of tetrahydroisohumulones

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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568344, 426600, C07C 4551

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046440844

ABSTRACT:
Tetrahydroisohumulones are prepared from beta-acids without using objectionable organic solvents by treating the beta-acids to form desoxytetrahydrohumulones which are dissolved in an aqueous alcoholic caustic solution and then oxidized and isomerized with an oxygen-containing gas in the presence of metallic ion to form the desired tetrahydroisohumulones.

REFERENCES:
patent: 3536495 (1970-10-01), Fly et al.
patent: 3552975 (1971-01-01), Worden et al.
patent: 3923897 (1975-12-01), Worden et al.
patent: 4002683 (1977-01-01), Todd, Jr.
patent: 4013721 (1977-03-01), Reininger et al.
patent: 4088688 (1978-05-01), Sigg-Grutter et al.
patent: 4160787 (1979-07-01), Moll et al.
patent: 4234516 (1980-11-01), Koller et al.
patent: 4395431 (1983-07-01), Lance et al.
The Merk Index, pp. 688 and 802, #4651 and #5422 (1983).

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