Process for producing amino acid

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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435106, 4352523, 43525231, 435822, 4351721, C12R 101, C12R 1304, C12R 1308

Patent

active

052178838

ABSTRACT:
Disclosed is a process for producing amino acids such as L-threohine and L-lysine, which comprises culturing, in a medium containing methanol as a major carbon source, a microorganism which belongs to the genus Methylobacillus and which has an ability to produce the amino acid(s) and resistance to at least one member selected from the group consisting of L-threonine, L-lysine and an amino acid analogue, said microorganism being obtained by mutation of a parent strain which belongs to the genus Methylobacillus and which has an enhanced sensitivity to at least one of an antibiotic and an amino acid analogue; allowing the amino acid(s) to accumulate in the culture; and recovering the amino acid(s) therefrom.

REFERENCES:
patent: 3907637 (1975-09-01), Nakayama et al.
patent: 3907641 (1975-09-01), Nakayama et al.
Japanese Patent Abstract No. 70-25273 "Production of Amino Acids by Fermentation".
APS JP0ABS Araki et al. Japan 01-235595 (Sep. 20, 1989).

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