Cocaine analogs

Details Cocaine analogs Cocaine analogs

1993-09-08

1995-02-21

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 14, 546124, C07F 702, C07F 940, C07D45112

Patent

active

053917448

ABSTRACT:
Bioactive cocaine analogs of the general formulae: ##STR1## are provided wherein X' is H or (C.sub.1 -C.sub.5)alkyl, X is H, halo, alkyl, alkoxy, perfluoroalkyl, nitro, alkoxycarbonyl, dialkoxyphosphonyl, acyl, perfluoroacyl, azido (substituted)silyl or (substituted)thio, and Y is H, halo, nitro, amino or (substituted)amino, alkoxycarbonyl, carboxy, alkyl or alkoxy; and the pharmaceutically acceptable salts thereof.

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J. A. Javitch et al., Mol. Pharmacol., 26, 35 (1985).
A. P. Kozikowski, Med. Chem. Res., 1, 312 (1991).

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