Purification of GM-CSF

Details Purification of GM-CSF Purification of GM-CSF

1993-09-21

1995-02-21

Parr, Margaret

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Lymphokines, e.g., interferons, interlukins, etc.

530397, 530416, 530417, 435 695, C07K 320

Patent

active

053917065

ABSTRACT:
A method of purifying granulocyte-macrophage colony-stimulating factor (GM-CSF), particularly recombinant human GM-CSF, in good yield and with retention of biological activity, comprising sequential anion-exchange, dye-ligand affinity, gel filtration and reversed-phase chromatography is disclosed.

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