Aromatic fluorine-containing organotin compounds and anti-tumour

Details Aromatic fluorine-containing organotin compounds and anti-tumour Aromatic fluorine-containing organotin compounds and anti-tumour

1995-08-24

1996-09-24

Nazario-Gonzales, Porfirio

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heavy metal containing doai

556 82, 556 90, 556 92, 556 94, 556105, A61K 3132, C07F 722

Patent

active

055591477

ABSTRACT:
The invention relates to novel aromatic fluorine-containing organotin compounds of the formula {(F.sub.5 C.sub.6 RCO.sub.2 SnBu.sub.2).sub.2 O}.sub.2 and {(F.sub.5 C.sub.6 RCO.sub.2).sub.2 SnBu.sub.2 } wherein R is CH.sub.2, CH.dbd.CH or a single bond between the phenyl ring and the CO.sub.2 group, and Bu is a butyl group; as well as to anti-tumour compositions containing as an active ingredient one or more of these compounds.

REFERENCES:
Moens et al, "Fungicidal Activity of a Series of Tri-and Diorganotin Compounds", Chemical Abstracts, Abstract No. 24470e, 1993.
Deacon et al, "Decarboxylation Syntheses of Some Polyfluo= Rophenyltin and--Germanium Compounds," Chemical Abstracts, Abstract No. 201657q, 1977.
Gielen et al, "Diorganotin Diflurobenzoates: Synthesis, Spec= Troacopic Characterization and In Vitro Antitumor Activity", Chemical Abstracts, Abstract No. 245345r, 1993.

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