Tricyclic anti-allergy, antiinflammatory and anti-hyperprolifera

Details Tricyclic anti-allergy, antiinflammatory and anti-hyperprolifera Tricyclic anti-allergy, antiinflammatory and anti-hyperprolifera

1988-06-17

1990-01-30

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514214, 514294, 540479, 540586, 546 94, A61K 3155, A61K 3133, C07D45504

Patent

active

048973912

ABSTRACT:
Isoquinolinone and isothiochromone derivatives of the general formula ##STR1## are disclosed. These compounds display anti-allergy, antiinflammatory and anti-hyperproliferative activity, which makes them useful for treating related disorders.

REFERENCES:
patent: 3824244 (1974-07-01), Houlihan et al.
patent: 4052508 (1977-10-01), Anderson et al.
Janssen, P. et al., Arzneim-Forsch. 15, 104-117(1965), Reprint, p. 3.
Coppola, G., J. Heterocyclic Chem., 18:767 (1980).
Shiraiwa, M. et al., Chem. Pharm. Bull. 31:2275 (1983).
Chem. Abstrs. 62:16179e (1965) [Desai, H. et al., J. Indian Chem Soc., 41(12), 821-9(1964)].
Desai, H. et al., J. Indian Chem. Soc., 41 (12), 821 (1964).
Derwent Abstract of DT 2,448,287, 4/17/75.

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