Process for controlling hyperlipidemia

Details Process for controlling hyperlipidemia Process for controlling hyperlipidemia

1985-10-17

1987-08-25

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514824, A61K 3155

Patent

active

046893261

ABSTRACT:
A process for controlling hyperlipidemia in mammals is disclosed. In this process a hyperlipidemia controlling effective amount of a compound having structural formula: ##STR1## where R.sup.1 is hydrogen, oxo, C.sub.1 -C.sub.6 alkyl or C.sub.2 -C.sub.6 alkanoyl; R.sup.2 is hydrogen or oxo; and R.sup.3 is hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 alkanoyl, C.sub.2 -C.sub.6 carboxyalkyl, phenyl, benzyl or phenyl substituted with C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 alkanoyl, C.sub.1 -C.sub.6 alkoxy or halo is applied to mammals. A pharmaceutical composition comprising the above class of compounds having the meanings given herein and a pharmaceutical carrier therefor is also taught.

REFERENCES:
patent: 2619484 (1952-11-01), Wenner
patent: 2693465 (1954-11-01), Schmidt et al.
patent: 3017337 (1962-01-01), Spiegelberg et al.
patent: 3075966 (1963-01-01), Hawthorne et al.
patent: 3116283 (1963-12-01), Boller et al.
patent: 3551414 (1970-12-01), Hawthorne et al.
patent: 3668232 (1972-06-01), Hawthorne et al.
patent: 3821201 (1974-06-01), Pessolano et al.
Journal of Pharmaceutical Sciences, vol. 73, No. 10, Oct. 1984, pp. 1482-1484; Chapman et al.

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