Test device, method of manufacturing same and method of determin

Details Test device, method of manufacturing same and method of determin Test device, method of manufacturing same and method of determin

1985-09-30

1987-08-25

Richman, Barry S.

Chemistry: analytical and immunological testing

Heterocyclic carbon compound

Hetero-o

422 56, 4273977, 435805, 436169, G01N 3352, G01N 3366

Patent

active

046893091

ABSTRACT:
A method of manufacturing the test device and method of determining the presence and relative concentration of a component in a test sample. The device includes a carrier matrix incorporated with a reactant system capable of interacting with a sample component to produce a detectable response. For home use, the reactant system produces a visibly detectable response. The carrier matrix of the device comprises a new and improved whole blood compatible, glucose-permeable strip or layer of a polymerizable silicone material. A reactant system is homogeneously mixed into the polymerizable carrier matrix prior to complete curing of the matrix, and the matrix then is cured to hold the reactant system homogeneously throughout the carrier matrix in a known concentration while maintaining matrix penetrability of the predetermined component after complete curing of the carrier matrix. The carrier matrix is formed from a dispersion of a polymerizable silicon-containing compound applied in an incompletely cured from in a liquid carrier containing a homogeneously mixed reactant system.

REFERENCES:
patent: 3418083 (1968-12-01), Rey et al.
patent: 3635679 (1972-01-01), Bloch et al.
patent: 4003707 (1977-01-01), Lubbers et al.
patent: 4327203 (1982-04-01), Deichert et al.
patent: 4495361 (1985-01-01), Friends et al.
patent: 4587101 (1986-05-01), Marsoner et al.

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