Method for drug administration

Details Method for drug administration Method for drug administration

1987-01-28

1988-12-20

Lusignan, Michael

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Food or edible as carrier for pharmaceutical

426613, 426660, A61K 968, A23D 500, A23G 300

Patent

active

047924497

ABSTRACT:
This invention relates to a method for administering drugs. In particular a lipophilic drug is solubilized by a food, such as chocolate, and admixed with an oil-based carrier. The lipid soluble drug is thus conveyed to the gastrointestinal tract. Because this type of food is digested readily, the drug is absorbed as intended, and the dose is not subject to day-to-day variations.

REFERENCES:
patent: 4609543 (1986-09-01), Morris et al.
Ota, B., "Administration of Cyclosporine", Transplantation Proceedings, vol. XV, No. 4, Suppl. 1 (Dec. 1983).
Kahan, B. D., Reid, M., and Newburger, J., "Pharmacokinetics of Cyclosporine in Human Renal Transplantation", Transplantation Proceedings, vol. XV, No. 1 (1983).
Schoenberg, L., Golden, D., Ota, B., Wideman, C., "Using Cyclosporine in Renal Transplantation", ANNA Journal, Oct. (1984).
Ptachcinski, R. J., Walker, S., Burckart, G. J., and Venkataramanan, R., "Stability and Availability of Cyclosporine Stored in Plastic Syringes", American Journal of Hospital Pharmacy, vol. 43, Mar. (1986).

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