Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-08-27
1993-10-12
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549330, 549362, 549366, 549397, 549398, 549414, A61K 3135, C07D30910
Patent
active
052525996
ABSTRACT:
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.
REFERENCES:
patent: 4486445 (1984-12-01), Patel et al.
patent: 4937373 (1990-06-01), Carson et al.
patent: 5124350 (1992-06-01), Djuric et al.
The Merck Index, 11th ed., 5154, p. 829 (1989).
Delorme Daniel
Dube Daniel
Ducharme Yves
Fortin Rejean
Gillard John W.
Cintins Marianne M.
Daniel Mark R.
DiPrima Joseph F.
Merck Frosst Canada Inc.
Muthard David A.
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