Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Patent
1991-08-21
1993-10-12
Kratz, Peter
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
422 55, 422 58, 435296, C12M 100, C12M 134
Patent
active
052524841
ABSTRACT:
A rapid method of determining the efficacy of a sterilization cycle, and an indicator adapted to perform such method, comprising subjecting to the sterilization cycle a source of active enzyme having activity which correlates with the viability of a microorganism commonly used to monitor sterilization, and incubating the enzyme source, following the completion of the sterilization cycle, with an effective amount of a substrate system capable of reacting with any residual active enzyme to produce a detectable enzyme-modified product.
REFERENCES:
patent: 2854384 (1958-09-01), Beakley et al.
patent: 3239429 (1966-03-01), Menolasino et al.
patent: 3346464 (1967-10-01), Ernst
patent: 3440144 (1969-04-01), Andersen
patent: 3551295 (1970-12-01), Dyer
patent: 3585112 (1971-06-01), Ernst
patent: 3661717 (1972-05-01), Nelson
patent: 3752743 (1973-08-01), Henshilwood
patent: 3796635 (1974-03-01), Delente
patent: 3846242 (1974-11-01), Ernst
patent: 4011139 (1977-03-01), Horwath et al.
patent: 4162942 (1979-07-01), Gunther
patent: 4284719 (1981-08-01), Agerhem et al.
patent: 4291122 (1981-09-01), Orelski
patent: 4304869 (1981-12-01), Dyke
patent: 4348209 (1982-09-01), Murtaugh et al.
patent: 4416984 (1983-11-01), Wheeler, Jr.
patent: 4448548 (1984-05-01), Foley
patent: 4461837 (1984-07-01), Karle et al,
patent: 4528268 (1985-07-01), Anderson et al.
patent: 4579823 (1986-04-01), Ryder
patent: 4580682 (1986-04-01), Gorski et al.
patent: 4591554 (1986-05-01), Koumura et al.
patent: 4596773 (1986-06-01), Wheeler, Jr.
patent: 4603108 (1986-07-01), Bascomb
patent: 4883641 (1989-11-01), Wicks et al.
patent: 5079144 (1992-01-01), Carr et al.
Roth, M., "Fluorimetric Assay of Enzymes", Methods of Biochemical Analysis, vol. 17, pp. 189-285.
"Fluorescence in Enzymology", Quantitative Assay of Enzymes, pp. 312-348.
Snyder, A. P. et al., "Pattern Recognition Analysis of In Vivo Enzyme-Substrate Fluorescence Velocities in Microorganism Detection and Identification", Appl. Environ. Microbiol., vol. 51, No. 5, pp. 969-977 (1986).
Laurence, D. J. R., "Fluorescence Techniques for the Enzymologist", Techniques for Characterization of Proteins, pp. 174-212.
Warth, A. D., "Heat Stability of Bacillus cereus Enzymes within Spores and in Extracts", Journal of Bacteriology, vol. 143, No. 1, pp. 27-34 (1980).
Yutani, K. et al., "Comparison of Thermostable .alpha.-Amylases from B. stearothermophilus Grown at Different Temperatures", J. Biochem., 74, pp. 573-579 (1973).
Suzuki, Y. et al., "Assignment of A p-Nitrophenyl .alpha.-D-Glucopyranosidase of Bacillus stearothermophilus ATCC 12016 to A Novel Exo-.alpha.-1,4-Glucosidase Active for Oligomaltosaccharides and .alpha.-Glucans", Biochemica et Biophysica Acta., 787, pp. 281-289 (1984).
Campbell, L. L. Jr., "Purification and Properties of an .alpha.-Amylase from Facultactive Thermophilic Bacteria", .alpha.-Amylase Studies, pp. 154-161.
Suzuki, Y. et al., "Production of Extracellular .alpha.-Glucosidase by a Thermophilic Bacillus Species, Applied and Environmental Microbiology", pp. 807-812 (1976).
Suzuki, Y. et al., "Purification and Properties of Extracellular .alpha.-Glucosidase of a Thermophile, Bacillus thermoglucosidius KP 1006", Biochimica et Biophysical Acta., 445, pp. 386-397 (1976).
Suzuki, Y. et al., "Assignment of A p-Nitrophenyl-.alpha.-D-Glucopyranoside-Hydrolyzing .alpha.-Glucosidase of Bacillus stearothermophilus ATCC 12016 to An Exo-Oligo.noteq.1,6-Glucosidase", Biochemica et Biophysics Acta., 704, pp. 476-483 (1982).
Warth, A. D., "Stabilization of Spore Enzymes to Heat by Reduction in Water Activity", Sporulation and Germination, Proceedings of the Eighth International Spore Conference, Woods Hole, Mass., pp. 249-252 (1980).
Priest, F. G., "Extracellular Enzyme Synthesis in the Genus Bacillus", Bacteriological Reviews, pp. 711-753 (1977).
Hodges, N. A., "A Comparison of Heat Resistance in Commercially Available Bacillus stearothermophilus Spore Preparations Used for Monitoring Steam Sterilization", J. Pharm. Pharmacol., 34, pp. 259-260 (1982).
Starkey, D. H., "The Use of Indicators For Quality Control of Sterilizing Processes in Hospital Practice: A Review", American Journal of Infection Control, vol. 8, No. 3, pp. 79-84 (1980).
Singleton et al., "Proteins from Thermophilic Microorganisms", Bacteriol Rev. 37, 320-42 (1973).
Wisdom et al., "Membranes of Bacillus stoarothermophilus: Factors Affecting Protoplast Stability and Thermostability of Alkaline Phosphatase and Reduced Nicotinamide Adenine Dinucleotide Oxidase", J. Baceriol. 114, 1336-45 (1973).
Foltz William E.
Matner Richard R.
Woodson Lewis P.
Boeder Jennie G.
Griswold Gary L.
Kirn Walter N.
Kratz Peter
Minnesota Mining and Manufacturing Company
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