Process for the resolution of enantiomers of benzopyran derivati

Details Process for the resolution of enantiomers of benzopyran derivati Process for the resolution of enantiomers of benzopyran derivati

1990-11-02

1992-04-07

Chan, Nicky

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D31178

Patent

active

051030250

ABSTRACT:
The invention relates to a process for the resolution of enantiomers of 3,4-epoxy-3,4-dihydro-2,2-dimethyl-3-R-2H-1-benzopyran-6-carbonitriles (I), in which R is H or CH.sub.3, characterized in that racemic I is dissolved in an inert solvent or solvent mixture together with a small amount of (-)-I [or (+)-I], the solution is seeded with (-)-I [or (+)-I], the precipitated (-)-I [or (+)-I] is isolated, further racemic I is dissolved in the filtrate, seeded with (+)-I [or (-)-I], the precipitated (+)-I [or (-)-I] is isolated and, if desired, this crystallization cycle is repeated one or more times.

Affiliated with

Also associated with

Rating

Process for the resolution of enantiomers of benzopyran derivati does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the resolution of enantiomers of benzopyran derivati, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the resolution of enantiomers of benzopyran derivati will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1896577